Chronotropic Incompetence in Heart Failure

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چکیده

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Chronotropic incompetence in heart failure.

The relationship between heart rate (HR) during exercise and exercise capacity in patients with heart failure due to left ventricular systolic dysfunction remains unclear. The accepted diagnostic criterion for chronotropic incompetence (CI), a maximum agepredicted heart rate (MA-PHR) 85%, is seen in 50% of patients with severe heart failure on contemporary medical therapy (1). Whether the lesse...

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Impaired heart rate recovery and chronotropic incompetence in patients with heart failure with preserved ejection fraction.

BACKGROUND This study assessed the chronotropic response to exercise and heart rate (HR) recovery after exercise in a carefully phenotyped group of patients with heart failure with preserved left ventricular ejection fraction (HfpEF) and a control group of similar age and gender distribution. METHODS AND RESULTS We studied 41 patients with HfpEF, 41 healthy controls, and 16 hypertensive contr...

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Rate responsive pacing using cardiac resynchronization therapy in patients with chronotropic incompetence and chronic heart failure.

AIMS Chronotropic incompetence (CI) is a common finding in patients with advanced chronic heart failure (CHF) and is associated with a worse functional capacity. Whether rate responsive pacing with cardiac resynchronization therapy (CRT) would acutely improve exercise performance in patients with advanced CHF and severe CI (<70% age-predicted maximum heart rate) is unknown. METHODS AND RESULT...

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Echocardiographic predictors of chronotropic incompetence to exercise in patients with heart failure with preserved ejection fraction.

OBJECTIVE Exercise intolerance in patients with heart failure with preserved ejection fraction (HFpEF) is most often attributed to diastolic dysfunction (DD); however, chronotropic incompetence (CI) could also play an important role. We intended to examine whether there are predictive echocardiographic parameters of DD for impaired chronotropic response to exercise. METHODS AND RESULTS Patien...

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Chronic heart failure, chronotropic incompetence, and the effects of beta blockade.

OBJECTIVE To establish the prevalence of chronotropic incompetence in a cohort of patients with chronic heart failure (CHF) taking modern medications for heart failure, and whether this affected exercise capacity and predicted prognosis. METHODS Heart rate response to exercise was examined in 237 patients with CHF in sinus rhythm, who were compared with 118 control volunteers. The percentage ...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2006

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2006.05.014